Benecol - Healthcare Professionals

Reference list for plant stanol ester publications.
Updated April 2010

  • General guidelines for lowering cholesterol
    Executive summary of the third report of the NCEP expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    Cleeman JL et al. JAMA. 2001 May 16;285(19):2486-97.
  • Subjects with metabolic syndrome
    A stanol yogurt drink alone or combined with a low-dose OTC statin lowers non-HDLc, but also lowers TGs & elevates HDLc in metabolic syndrome patients
    Plat J et al. ISA Rome 2006. We-P14:477.
  • Consumption frequency
    Effects on serum lipids, lipoproteins and fat soluble antioxidant concentrations of consumption frequency of margarines and shortenings enriched with plant stanol esters
    Plat J et al. Eur J Clin Nutr. 2000;54:671-7.
  • Postmenopausal women with and without coronary artery disease
    Changes in serum level and metabolism of cholesterol with plant stanol esters in postmenopausal women with and without coronary artery disease
    Gylling H et al. Menopause. 2006;13(2):286-93.
  • Adults with mild to moderate hypercholesterolaemia
    Cholesterol-Lowering Ability of a Phytostanol Softgel Supplement in Adults with Mild to Moderate Hypercholesterolemia
    Woodgate D et al. Lipids. 2006;41:127-32.
  • Patients after cardiac transplantation
    Regular Use of Margarine-Containing Stanol/Sterol Esters Reduces Total and Low-Density Lipoprotein (LDL) Cholesterol and Allows Reduction of Statin Therapy After Cardiac Transplantation: Preliminary Observations
    Vorlat A et al. J Heart Lung Transplant. 2003;22:1059-62.
  • Normocholesterolaemic and mildly hypercholesterolaemic subjects
    Plant stanol esters in low-fat yogurt reduces total and low-density lipoprotein cholesterol and low-density lipoprotein oxidation in normocholesterolemic and mildly hypercholesterolemic subjects
    Hyun YJ et al. Nutrition Research. 2005;25:743-53.
  • Plant stanol esters supplied in low-fat yogurt
    Effects of plant stanol esters supplied in low-fat yogurt on serum lipids and lipoproteins, non-cholesterol sterols and fat soluble antioxidant concentrations
    Mensink RP et al. Atherosclerosis. 2002;160:205-13.
  • Statin therapy
    Incremental reduction of serum total cholesterol and low-density lipoprotein cholesterol with the addition of plant stanol ester-containing spread to statin therapy
    Blair SN et al. Am J Cardiol. 2000 Jul 1;86(1):46-52.
  • Healthy diet
    Cholesterol-lowering effects of a stanol-ester containing low-fat margarine used in conjunction with a strict lipid-lowering diet
    Andersson A et al. Eur Heart J Suppl. 1999;1 Suppl S:S80-90.
  • Diabetic patients
    Serum cholesterol and cholesterol and lipoprotein metabolism in hypercholesterolaemic NIDDM patients before and during sitostanol ester-margarine treatment
    Gylling H and Miettinen T. Diabetologia. 1994;37:773-80.
  • Children
    Plant stanol ester margarine lowers serum total and low-density lipoprotein cholesterol concentrations of healthy children: the STRIP project
    Tammi A et al. J Pediatr. 2000;136:503-10.
  • Hypercholesterolaemic patients
    Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population
    Miettinen T et al. N Engl J Med. 1995;333:1308-12.
  • Dual effect
    Red cell and plasma plant sterols are related during consumption of plant stanol and sterol ester spreads in children with hypercholesterolemia
    Ketomäki AM et al. J Pediatr. 2003;142:524-31.

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